Excessive release of the pollutant carbon monoxide (CO) into

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Excessive release of the pollutant carbon monoxide (CO) into the air may produce a condition in which oxygen supply in the human body decreases. What causes this condition?

[UPSC CSE Prelims 2010]

When inhaled into the human body, CO is converted into CO2

The inhaled CO has much higher affinity for haemoglobin as compared to oxygen

The inhaled CO destroys the chemical structure of haemoglobin

The inhaled CO adversely affects the respiratory centre in the brain